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Dear Reader,
Policosanol is a substance
originally isolated from sugar cane wax and is also found in bee's wax,
rice bran, and wheat germ. A number of studies have found that sugar
cane policosanol lowers serum cholesterol levels as effectively as
various statin drugs. However, all published studies demonstrating a
beneficial effect of sugar cane policosanol have been authored by a
single research group from Cuba.
In a recent
study independent from the research group in Cuba, One hundred-forty
three patients with high Cholesterol were randomly assigned to receive,
in double-blind fashion, sugar cane policosanol (10, 20, 40, or 80
mg/day) or placebo for 12 weeks.
In none of the
five treatment groups did the LDL-cholesterol level decrease more than
10% from baseline. There were no statistically significant differences
between policosanol and placebo with respect to the changes in total-,
LDL-, or HDL-cholesterol, the ratio of LDL-cholesterol to
HDL-cholesterol, or triglyceride levels. A test analyzing
dose-dependency also yielded no significant results.
The results of the present study, as well as those of a similar study
using wheat germ policosanol suggest that policosanol is not an
effective treatment for high cholesterol.
Yours in good health,
Sheila McCormick
Editor, IVL Health Watch
http://www.IVLProducts.com From
research presented by Alan R. Gaby M.D., Literature Review and
Commentary. Dr. Gaby’s references noted were: Berthold HK, et al.
Effect of policosanol on lipid levels among patients with
hypercholesterolemia or combined hyperlipidemia: a randomized
controlled trial. JAMA. 2006;295:2262-2269.
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